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"The effects of human growth hormone and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology Publication confirming the effectiveness in body weight reduction and the mechanism of action

They can interact with some meds, like metformin and certain stomach acid drugs

Nothey dont dissolve fat cells

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Moreover, it has been recently proven that IGF-1 central administration also induced improvement in insulin sensitivity [291], meaning that this sudden rise after exercise or treatment could be of benefit not only in the periphery, but acting centrally